2023/07/28

The first assumed life form would have had to build several complex protein machines, otherwise life would not have continued

Life without DNA repair mechanisms is not possible


Many environmental factors, such as solar UV radiation, background radiation, and carcinogens, are highly harmful to the cell's DNA, leading to various types of damage. Some of these damages, if left unrepaired, can be fatally harmful, and even smaller errors, when accumulated, can cause severe diseases after just a few cell divisions. According to the theory of evolution, the first cells developed in a primordial soup, an environment where they would have been exposed to several harmful environmental factors. Without efficient DNA repair systems, the theorized first cell would not have been able to survive for long. To produce repair enzymes, mere DNA or RNA is not enough; it requires a precisely functioning machinery of protein production, guided and regulated by epigenetic mechanisms and factors. The hypothetical evolution would have halted at the point when the cell and its contained DNA needed to be duplicated. To achieve this, the first cell would have had to build complex replication machinery within its short lifetime. For instance, the active lifespan of bacteria is typically only a few days, so in a relatively short time, the first cell would have had to obtain a complex replication mechanism both for the cell and DNA to sustain life.

Science has also not yet determined how proteins that detect DNA errors can recognize grammatical errors in DNA. How can proteins recognize informative code? According to research, DNA's grammar is more complex than that of any known language.



DNA repair mechanisms are controlled by epigenetic mechanisms.

Life without DNA repair mechanisms ends quickly

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34173/

"Mice lacking a precise DNA repair activity have been generated, and these mutants show various combinations of defective embryogenesis, tissue-specific dysfunction, hypersensitivity to DNA-damaging agents, premature senescence, genetic instability, and elevated cancer rates. That repair-deficient animals display such abnormalities underscores the fundamental importance of DNA repair in protecting against the mutagenic and cytotoxic effects of DNA damage."

A question for evolution believers:

"How did the first presumed life form develop the cell's copying machinery and DNA repair systems during its own lifetime?"