The body's stress management is an irreducibly complex entity that has not been able to evolve

The body's stress management is an irreducibly complex entity that has not been able to evolve 

Our bodies constantly face different stress factors that can roughly be divided into physical and psychological stresses. Even walking from your warm home to a cold and damp, windy weather will cause a stress reaction in your skin because the skin's heat regulation proteins tend to balance heat fluctuations. If the mechanism does not work properly, you will not tolerate cold or hot.

To cope with stress situations, your body needs cortisol (hydrocortisone) produced by the cortex of the adrenal glands. The yield of cortisol is controlled by the mediator hormone ACTH, which in turn is produced by the pituitary gland. Hormone production of pituitary gland is in turn controlled by the CRH hormone produced by the hypothalamus and certain body cells. They also have an important link with our immune system. Also, intestinal bacteria have been found to have a clear connection with the production of CRH hormone.

Generally, producing cortisol is a highly regulated and controlled process because the body needs to get correct amounts of cortisol in the right time (over 140 tasks in a human body). Once the necessary control instructions have been given and cortisol released from the adrenal glands, a negative feedback loop guides the mechanism to suppress cortisol production at the time when the body responds to the stressor.

The following picture illustrates the mechanisms for stress management and the immune defense system and the connections between them. The system is irreducibly complex; even a disorder or problem in just one part of the system will collapse the whole system and the organism will die quickly. It is impossible for such a carefully regulated system, based on a number of elements, to evolve itself because the system works only as a complete entity.

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