2019/01/15

Genetic meltdown just in FIVE generations

DNA samples kept at museums reveal how rapidly genetic degradation can happen

https://earther.gizmodo.com/eastern-lowland-gorillas-heading-towards-genetic-meltdo-1831338998

Excerpts: "Needless to say, this is making an already bad situation for the Grauer’s gorilla even worse. But while the genetic diversity of these gorillas is plummeting, it has yet to reach the point of no return—a state known as “genetic meltdown,” after which time there isn’t enough diversity left in the gene pool for reproductive viability. There’s still time to bring these apes back from the brink, we just need to act.
 
Results confirmed a loss of genetic diversity among living Grauer’s gorillas, of which DNA samples were taking from seven individuals. What’s more, an alarming batch of genetic mutations have crept in over the past four to five generations—mutations that are making these gorillas more susceptible to communicable and genetic diseases, and less capable of adapting to environmental changes. Many of these mutations are classified as “Loss of Function” (LoF), which, as the name suggests, happens when a gene loses its evolved function. Over the last 100 years, Grauer’s gorillas have acquired several LoF mutations which, in humans and other related species, are related to changes in immune responses and male fertility. The researchers also detected LoF in genes associated with finger and toe development, which may explain why many living Grauer’s gorillas have fused digits."

My comment: Organisms need genetic rescue because evolution is not happening. And because museums keep a lot of ancient animal bones from previous generations, some scientists seriously try to use that ancient DNA to recover endangered species' genomes:

https://www.edge.org/response-detail/27232

Excerpt: "One further reservoir of genetic variability has yet to be employed. In museums throughout the world there are vast collections of specimens of species that have been reduced to genetically-impoverished remnant populations in the wild or in captive breeding programs. Those museum specimens are replete with “extinct alleles” in their preserved (though fragmented) DNA. Ancient-DNA sequencing and analysis is becoming so precise, the needed alleles can be identified, reproduced, and reintroduced to the gene pool of the current population, restoring its original genetic diversity. The long-dead can help rescue the needful living."

My comment: 
Mutational meltdown might occur very rapidly, just in five generations. Speciation can also happen just in two generations. Theories about millions of years of evolution are ridiculous fairytales. There is no mechanism for evolution. Every mutation is targeted to useful and functional DNA because there's no junk-DNA. Genetic entropy is a biological fact. Don't get lost.